Tomocube Microscope: Revolutionizing Imaging with 3D Holotomography
The Tomocube microscope utilizes 3D holotomography, an innovative imaging technique, to analyze samples. It measures the refractive index, or how light bends, through a sample to produce images without the need for dyes or fluorescent markers. This allows for 2D, 3D, and time-lapse imaging.
Holotomography (HT-X1): Ushering in a New Era of Microscopy
Imagine peering inside living cells, not just seeing their outlines, but understanding their very composition and dynamics, all without invasive dyes or labels. This is the promise of Holotomography (HT), and Tomocube is leading the charge in bringing this revolutionary technology to researchers worldwide.
What is Holotomography?
Holotomography is a cutting-edge microscopy technique that reconstructs live cells' and thin tissues' 3D refractive index (RI) distribution. In simple terms, it measures how light bends as it passes through a sample, revealing a wealth of structural and chemical information that traditional microscopy often misses.
Why is Refractive Index Important?
Refractive index (RI) is an intrinsic optical property of materials, meaning it's a fundamental characteristic of a substance. By mapping the RI distribution within a cell, HT provides insights into:
Dry mass: The amount of non-water components within the cell.
Morphology: The shape and structure of the cell.
Cellular membrane dynamics: How the cell's outer layer changes over time.
The Tomocube Advantage: Non-Invasive, Quantitative, and Fast
Tomocube's HT technology takes this concept and makes it accessible and powerful. Here's what sets it apart:
Non-invasive imaging: Because RI is an intrinsic property, HT eliminates the need for dyes or fluorescent markers, preserving the integrity of live cells and enabling long-term studies.
Quantitative data: HT provides precise, numerical data that can be used for detailed analysis and comparison.
Fast and easy: No extensive sample preparation is required, saving valuable time and resources.
3D visualization: Gain a complete three dimensional understanding of the sample.
Applications Across Disciplines
The ability to visualize and quantify cellular properties without invasive techniques opens up a world of possibilities for researchers in:
Cell biology
Microbiology
Drug discovery
Hematology
And beyond
Hollywood International Ltd. Team
The Future of Microscopy is Here
Holotomography, as pioneered by Tomocube, is transforming the way we study life at the cellular level. By providing a non-invasive, quantitative, and fast way to explore the inner workings of cells, it's paving the way for groundbreaking discoveries and a deeper understanding of biological processes.
