Our Team

Postdoctoral Fellow

PhD (Medicine)

I am interested in molecular biology and epigenetics in cancer. I working on 2 projects relating to synthetic lethality, biomarker discovery, and drug treatment in cancer. First, The Enhancement of Cell Cycle Inhibitors in Cholangiocarcinoma with epigenetic drug. Second, The Mechanism of recurrent oral cancer.

High-content Imaging Specialist

MSc (Plant Science)

My research has focused on System-based profiling in Asian cholangiocarcinoma. I successfully identified the best therapeutics and developed gene expression-based prognosis/predictive markers for cholangiocarcinoma subtype1 (CCA1). I am currently working on finding new treatment strategies to overcome resistance in the CCA1 subtype. I have also worked on the spatial biology of cholangiocarcinoma.

Primary Cell Culture Specialist

MSc (Genetics)

My project is to create patient-derived models of gynecological cancer for precision medicine studies and clinical use. I also focus on optimizing platforms, i.e. Comet assay and BH3 profiling, for predicting responses to standard and other promising targeted treatments in gynecological cancer patients.

Organoid and Cell Imaging Specialist

MSc (Medical biochemistry)

We are creating both 2D and 3D cell culture models that can be stored as live biobanks and are useful for identifying new effective cancer-targeting drugs or personalized drug prediction. Besides from establishing the models, I also use multiplex IF staining to perform morphological and phenotype signature evaluation and biomarker study to further support the relevance of these models.

Animal Model Laboratory Specialist

MSc (Pharmacology)

My research focused on exploring an acquired vulnerability of drug-resistant cholangiocarcinoma (CCA). Previous work discovered the combination of chemotherapy (GEM/CIS) plus anti-IAP drugs for overcoming drug resistance in CCA. Currently, I am working on ARID1A loss of function mutation by using CRISPR/Cas9 knockout to identify a new drug target for ARID1A mutated CCA.

Reversed Phase Protein Array Specialist

MSc (Biotechnology)

As a Reversed Phase Protein Array Specialist, I explore proteomic profiles in cancer, concentrating on drug discovery and understanding drug resistance mechanisms. Committed to advancing treatment strategies through comprehensive proteomic analysis to develop targeted treatment strategies for enhanced therapeutic outcomes.

Data Analyst

MEng (Biomedical Engineering)

As an oncology data analyst, my main focus is utilizing machine learning to identify cancer subtypes among Thai populations through gene expression profiles. Additionally, I provide proficient bioinformatic frameworks for proteomic data integration and analysis to support our scientists and specialists.

Immunohistochemistry Specialist

MSc (Anatomy)

I am interested in oxidative stress and antioxidants in skin aging models, both in vitro and in vivo. The interesting proteins and genes in mitochondrial energetics and redox signaling pathways were explored by using biomolecular techniques including mito stress test assay, ROS detection assay, immunofluorescence, and imaging.

MSc (Microbiology)

The current work is the study on the role of the epidermal microenvironment in the regulation of candidate proteins-modulated photoaging in dermal fibroblasts, the effects of PM 2.5 on mitochondria, and PM 2.5 regulates inflammation and apoptosis by cell culture and molecular technique. My next plan study herbs for cosmetic application.

MSc (immunology)

To do the research that studies of correlation of HIF-1 and vitamin D receptor in PM2.5 treated lung epithelial cells, I help with this research in part of RNA extraction, real-time PCR, immunofluorescence assay, and other parts. In the future, the study of Nrf2 and Vitamin D receptors. My responsibility is part of the ChlP assay.

MSc (Bioengineering)

My research experience includes cell cycle analysis via Edu staining, High-content imaging, in vitro viral assay, inhibitor screening for a viral disease, molecular cloning, viral RNA extraction, and Sequencing data analysis. My current work focuses on dengue viral RNA extraction and viral mutagenesis which contribute to severe disease.

Researcher in Cancer Immunotherapy

BSc (Pharmacy)

Our research focuses on the restoration of immune effector cells’ anti-tumor properties from their dysfunctionality state after exposure to cancer cells by small drug compounds using the cancer-immune co-culture system with time-lapse imaging.

Animal Laboratory Staff

BSc (Animal Science)

Assisting with the animal experimentation section of researchers' work involves controlling animal breeding, conducting experiments with the animals, and collecting samples from them for testing purposes.

Multiplex Tissue Imaging Staff

BSc (Biology)

My work is responsible for cancer diagnostics using multiplex tissue imaging, especially the t-CyCIF (tissue-based cyclic immunofluorescence) technique that generates multiplexed images of formalin-fixed, paraffin-embedded (FFPE) samples, and participating in research on biomarker development for predicting cancer prognosis and therapeutic response using archival specimens.

Data Analyst

MSc (Computational Biology)

As a bioinformatics data analyst, I specialize in classifying and subtyping cancer among Thai patients using gene expression profiles while developing a web application platform for aggregating potential cancer subtyping models to assist researchers and clinicians. Additionally, I support the development of analytical pipelines for other projects within the SiSP lab.